重组大鼠Eotaxin/CCL11

产品货号：

GS4623

中文名称：

重组大鼠Eotaxin/CCL11

英文名称：

Recombinant Rat Eotaxin/CCL11

产品规格：

5μg

发货周期：

1～3天

产品价格：

询价

分子量：Approximately 8.4kDa,a single non-glycosylated polypeptide chain containing 74 amino acids.
储存条件：冷冻（-20℃）

概述

CCL11 encoded by the gene CCL11is belonging to the CC chemokine family.It is a potent eosinophil chemoattractant that was originally purified from bronchoalveolar lavage fluid of guinea pigs sensitized by aerosol challenge with ovalbumin.CCL11 is a strong and specific eosinophil chemoattractant in vitro.It can directly chemotactic for eosinophils,but not for monocytes or neutrophils.CCR3 has been identified to be a specific CCL11 receptor.CCR3 has also been shown to serve as a cofactor for a restricted subset of primary HIV viruses and binding of CCL11 to CCR3 inhibited infection by the HIV isolates.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 0.1-1.0μg/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl.
内毒素	Less than 1 EU/μg of rRtEotaxin/CCL11 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	HPGSIPTSCC FTMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTKLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP

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